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We use a variety of Labs, but one that I commonly run is the Organix Profile, a complete quantitative organic acids test from Metametrix. The Organix provides a view into the body's cellular metabolic processes and the efficiency of metabolic function. Identifying metabolic blocks or problems with detoxification, gut dysbiosis, or oxidative stress that can be treated nutritionally allows for individual tailoring of interventions. Targeted treatment can help maximize patient responses and lead to improved patient outcomes.
Advantages of the Organix Comprehensive Profile
- Extensive Analyte List - The Organix Comprehensive contains one of the most extensive analyte lists in the industry. Including markers such as Quinolinate, D-Arabinitol, and 8-Hydroxy-2'deoxyguanosine, the Organix offers great value.
- Innovative Method - The LC/MS-MS method, which is also used to screen newborns for metabolic disorders, requires very little sample preparation and processing. This technology provides more stability, accuracy, and sensitivity in measuring organic acids at low levels for optimum test results.
- Single Urine Specimen - A single overnight urine collection is easy for patients, leading to increased patient compliance.
Why use an organic acid test?
Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, and intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This abnormality may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect. Testing for organic acids helps reveal activity and changes at the metabolic level, helping practitioners discover hidden issues and pinpoint where therapeutic focus is needed.
The Organix Profile provides important information in the areas of:
- Vitamin and mineral insufficiencies
- Amino acid insufficiencies like carnitine and N-acetyl cysteine (NAC)
- Oxidative damage and antioxidant sufficiency markers
- Indicators to assess detoxification sufficiency
- The best functional markers of B-complex deficiency
- Neurotransmitter metabolites to assess central nervous system (CNS) function
- Mitochondrial energy production assessment via citric acid cycle components
- Methylation sufficiency status
- Lipoic acid and CoQ10 sufficiency markers
- Specific dysbiosis markers for bacterial and yeast overgrowth
The Organix Profiles can provide important information for treating certain conditions, including:
- Fatigue
- Sleep abnormalities
- Mood changes
- Blood sugar dysregulation
- Weight gain
- Nausea
- Multiple chemical sensitivity
- Bloating
- Distention
- Joint pain
Analytes
FATTY ACID METABOLISM
Adipate
Suberate
Ethylmalonate
CARBOHYDRATE METABOLISM
Pyruvate
L-Lactate*
Beta-Hydroxybutyrate
ENERGY PRODUCTION (CITRIC ACID CYCLE)
Citrate
cis-Aconitate
Isocitrate
Alpha-Ketoglutarate
Succinate
Fumarate
Malate
Hydroxymethylglutarate
B-COMPLEX VITAMIN MARKERS
Alpha-Ketoisovalerate
Alpha-Ketoisocaproate
Alpha-Keto-Beta-Methylvalerate
Xanthurenate
Beta-Hydroxyisovalerate
METHYLATION COFACTOR MARKERS
Methylmalonate
Formiminoglutamate
NEUROTRANSMITTER METABOLISM MARKERS
Vanilmandelate
Homvanillate
5-hydroxyindoleacetate
Kynurenate
Quinolinate
Picolinate*
OXIDATIVE DAMAGE AND ANTIOXIDANT MARKERS
p-Hydroxyphenyllactate
8-Hydroxy-2'-deoxyguanosine*
DETOXIFICATON INDICATORS
2-Methylhippurate
Orotate
Glucarate
Alpha-Hydroxybutyrate
Pyroglutamate
Sulfate
BACTERIAL-GENERAL
Benzoate
Hippurate
Phenylacetate
Phenylpropionate
p-Hydroxybenzoate
p-Hydroxyphenylacetate
Indican
Tricarballylate
L.ACIDOPHILUS/GENERAL BACTERIA
D-Lactate*
CLOSTRIDIAL SPECIES
3,4 Dihydroxyphenylpropionate
YEAST/FUNGAL
D-Arabinitol*
Creatinine
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Cayer Chiropractic and Nutritional Health Center
97 South Main Street
Newtown, CT 06470
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97 South Main Street
Newtown, CT 06470
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